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A MyLupusTeam Member asked a question 💭
Gymea Bay, AU
January 21
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How is Cymbalta used for lupus?

Cymbalta (duloxetine) is an antidepressant that can help manage several symptoms that people with lupus commonly experience. It works by increasing levels of serotonin and norepinephrine in the brain, which help regulate mood and manage pain.

While originally approved for major depressive Show Full Answer

How is Cymbalta used for lupus?

Cymbalta (duloxetine) is an antidepressant that can help manage several symptoms that people with lupus commonly experience. It works by increasing levels of serotonin and norepinephrine in the brain, which help regulate mood and manage pain.

While originally approved for major depressive disorder, duloxetine is now also used for:
* Generalized anxiety disorder
* Chronic pain conditions like fibromyalgia
* Musculoskeletal pain
* Neuropathic (nerve) pain

Many people with lupus experience depression and various types of pain, making duloxetine a helpful option. Some members have found it beneficial, though like all medications, it can cause side effects.

One important thing to be aware of: duloxetine can cause fatigue as a side effect, which can be confusing since fatigue is already a common lupus symptom. It can also interact with NSAIDs (like ibuprofen and naproxen), which many people with lupus take for pain and inflammation.

If you're considering duloxetine or already taking it, talk with your healthcare provider about potential interactions with your other medications and how to manage any side effects you might experience.

January 21

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