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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

for the first time, I been having a low level flare that I can’t seem to shake. I have done the prednisone 20mg 15mg 10 and 5. Any thoughts

A MyLupusTeam Member asked a question 💭
Westchester, NY

Obviously I in contact with Dr.

February 7
 · 
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A MyLupusTeam Member

Indomethacin can injure the kidneys, so those with kidney disease cannot take it.

Please get extra rest, Mike, as that often helps. The other usual measures of UV avoidance, healthy eating, and stress reduction help, too. I hope you get better soon!

February 7
A MyLupusTeam Member

Thanks for your kind

February 7
A MyLupusTeam Member

Its very hard in your system but have you tried indomethacin? Its a very strong anti-inflammatory but but I use it occasionally when I have a flare that doesn't want to break. Its hard on the stomach so if you have issues with that they may not prescribe it.

February 7
MyLupusTeam

How can you manage a persistent low-level lupus flare that isn't responding to prednisone tapering?

It's frustrating when a flare lingers despite trying different prednisone doses. Since you're already working with your doctor, that's the right approach—persistent flares that don't improve may signal that your lupus isn't Show Full Answer

How can you manage a persistent low-level lupus flare that isn't responding to prednisone tapering?

It's frustrating when a flare lingers despite trying different prednisone doses. Since you're already working with your doctor, that's the right approach—persistent flares that don't improve may signal that your lupus isn't fully controlled and your treatment plan needs adjustment.

Here are some things to consider discussing with your rheumatologist:

- Your current dose range (20mg down to 5mg) falls in the low to medium range, which is typically used for flare management
- If symptoms persist, your doctor might need to adjust your medication regimen beyond just prednisone
- Sometimes adding or changing other immunosuppressive medications can help when prednisone alone isn't enough

A MyLupusTeam member shared a similar experience: "I get this with severe flares. It lasts for days" and noted it happened both before and after starting medications, highlighting how flares can be stubborn.

While waiting to see your doctor, focus on identifying and avoiding potential triggers—stress, certain foods, overexertion, or sun exposure can all prolong flares. Rest is also crucial during this time.

Since your flare isn't resolving as expected, be sure to communicate this clearly to your doctor. Repeated or persistent flares often indicate it's time to modify your treatment approach rather than just adjusting prednisone doses.

February 7

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