Can lupus cause muscle twitching?
Yes, muscle twitching can occur with lupus, though it's not one of the most common symptoms. Many MyLupusTeam members experience involuntary muscle spasms in various parts of their body.
The twitching can feel different for everyone:
- Tiny one-time spasms in calves, ankles, and thighs
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Can lupus cause muscle twitching?
Yes, muscle twitching can occur with lupus, though it's not one of the most common symptoms. Many MyLupusTeam members experience involuntary muscle spasms in various parts of their body.
The twitching can feel different for everyone:
- Tiny one-time spasms in calves, ankles, and thighs
- Uncontrollable twitching in legs, arms, and torso
- Painful intercostal muscle spasms that make breathing difficult
- Body jerking when relaxed or falling asleep
Some members notice their twitches get worse during lupus flares or when symptoms are more active. The movements can happen daily for some people, while others experience them occasionally or in response to certain triggers.
Lupus and antiphospholipid syndrome (another autoimmune condition associated with lupus) are both connected with movement disorders. Scientists believe this happens when autoantibodies attack nerve cells in the brain that control movement. What might be causing the twitching?
Several factors could contribute to muscle twitching with lupus:
Lupus-related causes:
- Neuropsychiatric lupus affecting nerve cells
- Lupus myositis (muscle inflammation)
- Peripheral neuropathy from nerve damage
Medication side effects:
- Corticosteroids like prednisone
- Immunosuppressants such as cyclosporine or cyclophosphamide
- Hydroxychloroquine
- Gabapentin
Other factors:
- Low magnesium levels
- Dehydration
- Stress or fatigue
- Too much caffeine
If you've recently started new medications and noticed twitching, talk to your doctor or rheumatologist about whether this could be a side effect. When should you see a doctor?
If your muscle twitching is frequent or bothersome, it's time to speak with your doctor. They can help determine the cause and find the best treatment for you.
Your rheumatologist may refer you to a neurologist for blood tests or scans to screen for nervous system problems. They might also check your magnesium levels, as many members have found that low magnesium contributes to muscle cramping.
Don't start any new supplements, including magnesium, without your doctor's approval. They can confirm if your levels are low and guide you on the right dosage.
While occasional muscle twitching is fairly common in people with lupus, tracking your symptoms and discussing them with your healthcare team can help you better understand what works for your body.
March 7
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