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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
April 9
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MyLupusTeam

Is it normal to have swelling after a Benlysta injection?

A lump or swelling at the injection site is actually a common reaction. It's basically your immune system responding to the medication and sending extra attention to that area. Most injection site lumps are temporary and nothing to worry about.

Here's what you can do Show Full Answer

Is it normal to have swelling after a Benlysta injection?

A lump or swelling at the injection site is actually a common reaction. It's basically your immune system responding to the medication and sending extra attention to that area. Most injection site lumps are temporary and nothing to worry about.

Here's what you can do to help it heal:

- Apply a warm compress to help with blood flow and reduce swelling
- Gently massage around the area (not directly on it)
- Take over-the-counter pain relief if it's sore
- Keep moving with gentle exercise to boost circulation
- Rotate your injection sites to give your skin a break

Most lumps like this disappear within a few days to two weeks.

However, you should contact your doctor if:

- The swelling is still there after two weeks
- It becomes red, purple, hot, or increasingly painful
- You develop any signs of infection

Since this is your first time experiencing this reaction with Benlysta, it's worth mentioning to your healthcare provider at your next appointment, even if it resolves on its own. They can provide guidance specific to your situation.

April 9

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