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April 25
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A MyLupusTeam Member

Yes and yes to this.. Sjogren's was my first diagnosis then SLE years later

April 28
MyLupusTeam

Great questions! Let's tackle both of these together.

Lupus and Sjögren's Disease

Sjögren's disease is indeed a known comorbidity of lupus. Estimates suggest that between 14% and 17.8% of people with lupus also develop Sjögren's disease. So while it's not a guarantee, it's not uncommon either.

Both conditions share Show Full Answer

Great questions! Let's tackle both of these together.

Lupus and Sjögren's Disease

Sjögren's disease is indeed a known comorbidity of lupus. Estimates suggest that between 14% and 17.8% of people with lupus also develop Sjögren's disease. So while it's not a guarantee, it's not uncommon either.

Both conditions share inflammation as a common thread, which is why symptoms can sometimes overlap — things like joint pain, skin rashes, and kidney problems can appear in both. Sjögren's also tends to bring its own signature symptoms like dry eyes and dry mouth.

A MyLupusTeam member shared: *"I have Sjögren's, lupus, and vitiligo."* Many others on the team have navigated both diagnoses too.

If there's any concern about Sjögren's, a rheumatologist is the best person to evaluate and manage both conditions. Can Lupus Cause Anemia?

Absolutely — anemia is actually one of the most common blood-related issues in lupus, affecting up to 50% of people with SLE at some point. There are several types to be aware of:

- Anemia of chronic disease — The most common type. Long-term inflammation from lupus can prevent bone marrow from making enough red blood cells, even when iron levels look normal.
- Iron-deficiency anemia — Affects about one-third of people with SLE. Inflammation can make it harder to absorb iron, and kidney involvement can cause iron loss through urine.
- Autoimmune hemolytic anemia — A rarer but more serious type where the immune system attacks red blood cells directly, affecting around 10% of people with SLE.
- Drug-induced anemia — Some lupus medications, like immunosuppressants, can affect how well bone marrow produces red blood cells.

Common symptoms across these types include fatigue, shortness of breath, dizziness, and pale skin. A simple blood test (CBC) can help identify what's going on.

It's always worth flagging any new or worsening fatigue or other symptoms to a healthcare provider, as treating the underlying lupus activity often helps improve anemia too.

April 25

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