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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
May 24
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A MyLupusTeam Member

Please notify your doctor as soon as possible tomorrow. Also, be aware of the side effects of Methotrexate. It is important to know the side effects of all our medications so that we know what to look for. It is a form of advocating for yourself. Especially since it's so easy for our doctors to blame everything on lupus before considering that it is from a medication. Not even our doctors can remember every side effect of the medications they prescribe. Please keep us updated.💜

May 25
MyLupusTeam

An itchy rash on the thigh without sun exposure is definitely something that can happen with lupus — sun isn't always the trigger. There are a few types of lupus-related rashes that could show up on the legs and cause itching.

Here are some possibilities worth discussing with a doctor or dermatologist:

- Discoid lupus (DLE) — Show Full Answer

An itchy rash on the thigh without sun exposure is definitely something that can happen with lupus — sun isn't always the trigger. There are a few types of lupus-related rashes that could show up on the legs and cause itching.

Here are some possibilities worth discussing with a doctor or dermatologist:

- Discoid lupus (DLE) — Round, thick, scaly patches that can itch or hurt and may lead to scarring if scratched
- Subacute cutaneous lupus (SCLE) — Circular red patches with a ring-like border, sometimes scaly
- Hives (urticarial vasculitis) — Itchy welts that can be linked to lupus, especially if they last more than a day
- Lupus flare-up — A flare can trigger skin symptoms even without UV exposure

Other triggers beyond sun exposure include certain medications, smoking, and general flare activity. A MyLupusTeam member shared that they get lesions on their lower legs that itch so intensely that scratching breaks the skin and causes bruising — so the struggle is very real and very common.

A dermatologist can do a skin biopsy to get a clearer picture of what's going on. It's worth bringing this up with a rheumatologist or dermatologist, especially if the rash is new, spreading, or getting more uncomfortable.

May 24
A MyLupusTeam Member

I took myself off Methotrexate after both the pharmacist and my Internist confirmed it was likely an allergic reaction. My rheumatologist wouldn't respond to my calls or messages. I have since found a rheumatologist who seems more committed to her patients at Prisma in Columbia SC. The big medical school (MUSC) Fellow clearly just didn't care. It definitely helped me make up my mind about cutting Dr. King as a treatment provider.

May 26
A MyLupusTeam Member

Hi Patricia
I have those spots on my legs, my Dermatologist said it's cutaneous lupus. They itch and flare up at times, especially in the summer. I was given triamcinocolone. Unfortunately I was told not to remove them because they will come back and they are not 100% sure this happens to Lupus patients. I had beautiful legs, but they scared

August 14
A MyLupusTeam Member

Since I had a very bad allergic reaction to Methotrexate, I have been getting occasional itchy bumps. I'm hoping this isn't the new normal. This is where my allergic rash started on my neck. It spread all over my body. Two weeks ago, it finally calmed down, but I keep getting lone itchy bumps.

May 24

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