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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Have any of you had neuropathy get worse while taking magnesium oxide? I don’t take gabapentin at the same time. But have taken it a while

A MyLupusTeam Member asked a question 💭
NC

And it seem numbness is worse

July 12
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MyLupusTeam

That's a really important observation to bring up with a doctor. Worsening numbness is worth taking seriously, especially when living with lupus, since nerve complications are a known part of the condition.

Neuropathy in lupus can sometimes progress on its own, independent of supplements or medications. Magnesium oxide isn't Show Full Answer

That's a really important observation to bring up with a doctor. Worsening numbness is worth taking seriously, especially when living with lupus, since nerve complications are a known part of the condition.

Neuropathy in lupus can sometimes progress on its own, independent of supplements or medications. Magnesium oxide isn't commonly linked to worsening neuropathy, but everyone's body responds differently. Some things worth discussing with a healthcare provider include:

- Whether lupus-related nerve involvement has progressed — this can happen over time and may need reassessment
- Whether magnesium oxide could be interacting with anything else being taken
- Whether a different treatment approach for the neuropathy might be more effective now

Gabapentin is one option some people with lupus use for nerve pain relief, and many MyLupusTeam members have shared positive experiences with it — though it does carry its own risks worth weighing carefully with a doctor.

Bringing up the timeline of when the numbness worsened relative to starting magnesium oxide will help the doctor piece things together more clearly.

July 12
A MyLupusTeam Member

My neuropathy has really amped up, it's 24/7 now in all limbs. I take magnesium glycinate at night to sleep. I don't know if that's why or if it's because the SLE isn't under control. I hope you find an answer and relief. I'm praying for you sister💜

July 12
A MyLupusTeam Member

It’s safe to take but not at the same time. They need to be hours apart. I would suggest a magnesium complex cause it has 8 forms of magnesium and it is good for neuropathy for most people but you can’t take them together.

July 12
A MyLupusTeam Member

Frankie, I suggest you double-check with your neurologist about whether the combo is safe.

July 12
A MyLupusTeam Member

I think one time my neurologist said to not take magnesium because of interference with gabapentin but now I don’t remember. That’s been a while back.

July 12

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