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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
August 21
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MyLupusTeam

MGUS (monoclonal gammopathy of undetermined significance) is not a direct comorbidity of lupus, so it falls outside the scope of what can be helpfully addressed here for managing lupus specifically.

What can be said is that lupus itself involves immune system irregularities, including abnormal antibody production, which can Show Full Answer

MGUS (monoclonal gammopathy of undetermined significance) is not a direct comorbidity of lupus, so it falls outside the scope of what can be helpfully addressed here for managing lupus specifically.

What can be said is that lupus itself involves immune system irregularities, including abnormal antibody production, which can sometimes complicate lab results and overlap with other conditions involving proteins in the blood.

If you're experiencing concerns about MGUS alongside lupus, the most important step is to speak with your rheumatologist and hematologist together, so they can coordinate care and make sure treatments for one condition don't negatively impact the other.

Some key things to discuss with your care team:

- Whether any medications used for lupus could interact with monitoring or treatment for MGUS
- How to interpret lab results that may be affected by both conditions
- A shared care plan between your specialists

Your doctors are really the best resource here since this is a nuanced situation that needs personalized medical guidance.

August 21

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