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So, obviously, I'm taking hydroxychloroquine, but I recently stopped taking my vitamins and supplements due to sudden allergic reactions. But now, what about Tylenol or Motrin? Are they okay to take while taking hydroxychloroquine?

June 14, 2025
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A MyLupusTeam Member

I agree with AI, Bmack. Tylenol is safe for most of us unless we have advanced liver disease, but with kidney disease, any other over-the-counter pain meds can cause further kidney damage. Please check with your doctor.

June 15, 2025
MyLupusTeam

Yes, you can generally take both Tylenol (acetaminophen) and Motrin (ibuprofen) while on hydroxychloroquine. Many people with lupus safely combine these medications. However, if you have lupus nephritis or kidney disease, your doctor may specifically recommend acetaminophen over NSAIDs like Motrin. While these medications Show Full Answer

Yes, you can generally take both Tylenol (acetaminophen) and Motrin (ibuprofen) while on hydroxychloroquine. Many people with lupus safely combine these medications. However, if you have lupus nephritis or kidney disease, your doctor may specifically recommend acetaminophen over NSAIDs like Motrin. While these medications are typically safe to combine, it's important to get personalized medical advice before starting any new medication - even over-the-counter ones. Your doctor or pharmacist can help determine the safest pain relief options based on your specific health conditions and other medications you may be taking.

June 14, 2025

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Miami Shores, FL