How does lupus affect blood pressure?
Lupus can significantly impact your blood pressure, and up to half of people with lupus develop high blood pressure. This connection happens in several ways.
Chronic inflammation from lupus can damage blood vessels and contribute to plaque buildup inside arteries, making them stiff or Show Full Answer
How does lupus affect blood pressure?
Lupus can significantly impact your blood pressure, and up to half of people with lupus develop high blood pressure. This connection happens in several ways.
Chronic inflammation from lupus can damage blood vessels and contribute to plaque buildup inside arteries, making them stiff or narrow. This reduces blood flow and can increase blood pressure.
High blood pressure may signal a lupus flare-up or indicate damage to important organs like your kidneys. When lupus affects the kidneys (lupus nephritis), they can't filter waste and fluids effectively, leading to fluid retention and elevated blood pressure.
A MyLupusTeam member shared: "Any time my body is out of whack, my blood pressure tends to rise some. The doctor said that it was my body's response to the inflammatory process."
Some lupus medications, particularly corticosteroids, can also raise blood pressure. However, hydroxychloroquine (Plaquenil) has been shown to reduce blood clot risk by 49 percent.
For people with lupus, keeping blood pressure below 130/80 mm Hg is recommended, as higher readings increase the risk of heart attack, stroke, and other cardiovascular complications.
Regular monitoring and working closely with your healthcare team to manage both lupus and blood pressure is essential for protecting your heart and overall health.
December 1, 2025
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