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I've been on it 8 months and it's really helped my pain, but I've somehow never felt worse.

July 16
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A MyLupusTeam Member

Go see a counselor.

July 17
MyLupusTeam

It's really tough to feel like one problem is being solved while another is creeping in — and you're definitely not alone in this experience. Several MyLupusTeam members have reported similar feelings while on hydroxychloroquine.

Fatigue, muscle weakness, and depression are actually listed as serious side effects of Show Full Answer

It's really tough to feel like one problem is being solved while another is creeping in — and you're definitely not alone in this experience. Several MyLupusTeam members have reported similar feelings while on hydroxychloroquine.

Fatigue, muscle weakness, and depression are actually listed as serious side effects of hydroxychloroquine. While they're not the most common, they are recognized and worth taking seriously — especially since you've been experiencing this for 8 months. Here's what's worth knowing:

- Fatigue and low energy can be a direct side effect of hydroxychloroquine
- Depression is also a recognized serious side effect
- These two can feed into each other, making daily life feel really heavy
- Fatigue and weakness can also make it harder to stay active, which can worsen mood over time

The good news is that hydroxychloroquine is clearly doing something right for your pain. That doesn't mean you have to just put up with feeling emotionally flat and exhausted though.

It's really important to bring this up with your doctor as soon as possible. They can assess whether these symptoms are linked to the medication and explore options — whether that's adjusting the dose, adding support, or considering other approaches. You deserve to feel better in *all* the ways, not just one.

July 16

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York, NE